Healthcare with Confidence
Leading Oral and Maxillofacial Surgeon in Israel
Position: Attending Surgeon and Head of Laboratory for Oral Cancer Research
Hospital: Rambam Health Care Campus (Rambam Medical Center), Haifa, Israel
Dr. Yoav Leiser is award-winning surgeon recognized for contributions to maxillofacial surgery and cancer research in Israel. He has unique triple degree (DMD, PhD, MD) and serving as head of the Research Laboratory with active study program focusing on heparanase expression in oral malignancies. As Dental Specialist, also he is specialized in immediate load implants (teeth in one day) using advanced AI scanning and laser-printed titanium technologies.
Dr. Yoav Leiser is included in Forbes list of the best Israeli doctors
Qualified Medical Consultation, Second Opinion
Qualified Medical Consultation by Oncologic Maxillofacial Surgeon Yoav Leiser
Clinical Specializations:
- Oral and Head-Neck Oncology: Surgical management of oral squamous cell carcinoma, head and neck tumors, malignant salivary gland diseases
- Surgical Oncology: Tumor resection, oncologic reconstruction, margins assessment
- Craniofacial Surgery: Complex facial reconstruction, post-traumatic facial surgery, esthetic outcomes
- Implant Surgery: Advanced dental implantology, immediate load implants, complex bone augmentation, sinus lift procedures
- Reconstructive Surgery: Maxillofacial restoration, esthetic reconstruction
- Oral Surgery: Extraction of complex teeth, biopsies, diagnostic procedures
- Anxiety Management: Licensed hypnosis therapy for managing dental phobias and patient anxiety
- Advanced Technology: AI-powered scan technology, laser-printed titanium implants for extreme bone deficiency
Research Specializations:
- Tumor Biology: Heparanase expression and localization in oral cancer
- Prognostic Markers: Gene expression patterns, hypoxic signaling pathways
- Molecular Biology: Cell invasion mechanisms, tumor microenvironment
- Cancer Prevention: Risk factors and prevention strategies in oral malignancies
- Therapeutic Development: Cancer cell invasion inhibition, experimental therapeutic approaches
- Biomarkers: Salivary and tissue biomarkers for cancer diagnosis and prognosis
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Education
Dental Medicine Degree
- 2004: DMD (Doctor of Dental Medicine), Faculty of Dental Medicine, Hebrew University Hadassah Ein Kerem, Jerusalem, Israel
Doctoral Degree
- 2005: PhD (Molecular Biology), Hebrew University, Jerusalem, Israel
- Dissertation Focus: Gene expression and hypoxic signaling pathways in oral cancer
- Supervisor: Prof. Israel Vlodavsky, Institute for Cancer and Vascular Research
Medical Degree
- 2018: MD (Doctor of Medicine), Faculty of Medicine, Tel Aviv University, Israel
Specialty Training
- Residency: Oral and Maxillofacial Surgery, Rambam Health Care Campus, Haifa, Israel
Advanced Research Training
- 2009-2010: Postdoctoral Fellowship, Institute for Cancer and Vascular Research, Technion – Rappaport Faculty of Medicine
- Focus: Prognostic role of heparanase gene in oral cancer
- Supervisor: Prof. Israel Vlodavsky
Professional Certifications
- Israeli Hypnosis License: Ministry of Health certification for clinical hypnosis therapy in dental practice
Professional Experience of Dr. Leiser
Rambam Health Care Campus, Haifa, Israel
- 2010 – Present: Attending Surgeon, Department of Oral and Maxillofacial Surgery
- 2012 – Present: Head of Laboratory for Oral Cancer Research
- Responsibilities:
- Surgical management of oral cancer cases
- Direction and supervision of cancer research laboratory
- Supervision of M.Sc. and PhD graduate students in basic science research
- Clinical training of residents in oral and maxillofacial surgery
Dr. Yoav Leiser Private Clinic, Haifa, Israel
- 2010 – Present: Founder and Director
- Focus:
- Comprehensive maxillofacial surgical services
- Specialized dental implantology with advanced technology
- Immediate load implants (teeth in one day procedures)
- AI-powered scanning and laser-printed titanium implants for complex cases
- Anxiety management through clinical hypnosis
- Esthetic reconstruction
Academic Appointments & Teaching
Technion – Israel Institute of Technology, Rappaport Faculty of Medicine, Haifa
- Current: Lecturer and Clinical Counselor
- Teaching Responsibilities:
- Preclinical and clinical medical education
- Supervision of medical students
- Lectures on oral cancer and surgical techniques
- Mentoring of advanced students
Rambam Health Care Campus – Educational Activities
- Postgraduate Education: Instructor in oral and maxillofacial surgery courses
- Research Supervision: Guidance of M.Sc. and PhD candidates in cancer research
- Clinical Education: Training of dental and medical residents
Research & Publications
Research Laboratory: Head of Oral Cancer Research Laboratory, Rambam Medical Center
Research Interests:
- Heparanase expression in oral malignancies
- Prognostic markers in head and neck cancer
- Molecular mechanisms of tumor invasion
- Cancer-related gene expression patterns
- Hypoxia-induced signaling in oral cancer
- Salivary biomarkers for cancer diagnosis
- Therapeutic targeting of cancer cell invasion
Selected Key Publications (30+ total in peer-reviewed journals):
- Leiser Y, Vlodavsky I, Peled M. “Prognostic value of heparanase expression and cellular localization in oral cancer.” Head & Neck, 33(10):1487-1497.
- Leiser Y, Abu El Naaj I, Yehudai N, Peled M. “Airway Management in Oral Cancer Surgery.” Oral Oncology, 47 Supplement 1:S145-S146.
- Leiser Y, Papageorgis P, Edorovitch T, Abu El Naaj I, Vlodavsky I, Peled M. “Heparanase is a reliable marker of squamous cell carcinoma of the oral cavity and its expression predicts patient outcome.” Journal of Cancer Research and Clinical Oncology.
- Leiser Y, Peled M. “The Management of Maxillary Squamous Cell Carcinoma―A Retrospective Study.” International Journal of Oral & Maxillofacial Surgery.
- Leiser Y, Vlodavsky I. “Does long-term treatment with Doxil® predispose patients to oral cancer?” International Journal of Clinical Oncology, 16(3):260-265.
- Abu El Naaj I, Leiser Y, Peled M. “Oral and maxillofacial considerations in patients receiving chemotherapy.” Journal of Oral and Maxillofacial Surgery.
- Leiser Y, Yehudai N, Peled M, Vlodavsky I. “Heparanase expression correlates with poor survival in oral mucosal melanoma.” Oral Oncology, 49(12):1162-1169.
- Leiser Y, Peled M. “Immediate Loading Implants in Maxillary Defects: Clinical Outcomes and Reconstruction Strategies.” Journal of Oral and Maxillofacial Surgery.
Conference Presentations: 40+ lectures and presentations at international and national scientific conferences
Professional Memberships & Affiliations
Israeli Professional Organizations:
- Member, Israel Dental Association
- Member, Israel Medical Association
- Member, Israel Society of Oral and Maxillofacial Surgery
- Member, Israel Society of Head and Neck Surgery and Oncology
- Member, Israel Cancer Association
International Professional Organizations:
- Member, International Association of Oral and Maxillofacial Surgery (IAOOS)
- Member, International Academy of Oral Oncology (IAOO)
- Member, European Association for Cranio-Maxillofacial Surgery
Editorial and Review Roles:
- Reviewer for international peer-reviewed journals in maxillofacial surgery and oncology
- Editor, multiple clinical and research journals in his specialty
Awards & Recognition
Research Awards:
- 2011: Wolf Foundation Award for Exceptional Doctoral Studies
- 2011: Best Abstract Award, Israeli Society of Head and Neck Surgery
- 2009-2010: Itay Sharon “Rambam Atidim” Grant – Principal Investigator
- Awarded for postdoctoral research on heparanase in oral cancer
Clinical Recognition:
- 2010: John Lowry Prize for Oral and Maxillofacial Trainees
- Awarded by XX Congress of the European Association for Cranio-Maxillofacial Surgery, Bruges, Belgium
- 2015: Outstanding Lecturer, Technion Faculty of Medicine, “Being a Doctor” Course (Undergraduate)
- Recognition as leading researcher in oral cancer and maxillofacial oncology
- Multiple research grants and institutional recognitions
Languages
- Hebrew
- English
Patients’ highlights about Surgeon Leiser
Dr. Yoav Leiser combines cutting-edge surgical techniques with evidence-based oncologic principles. His practice emphasizes:
- Comprehensive cancer treatment with optimal survival outcomes
- Functional and esthetic reconstruction
- Advanced patient assessment and risk stratification
- Innovation in implant technology and immediate loading
- Patient-centered care with anxiety management
- Integration of basic research findings into clinical practice
- Multidisciplinary collaboration with oncology teams
- Commitment to training the next generation of surgeons
Additional Professional Activities
Artistic Endeavors:
- Active practice of sculpture and woodcarving as a creative outlet
- Artistic education: 1987-1995 woodcarving study and practice; 1995-1997 professional workshop training with Hans Yuachin Kantor, Neve Zedek, Tel Aviv
