Kidney cancer – is the uncontrolled division of abnormal cells of the kidneys, that create tumor. Two most common types of kidney cancer is renal cell carcinoma (RCC) and urothelial carcinoma (UCC) of the renal pelvis. These names reflect the type of cell from which the cancer develops.
The leading Israeli experts in renal cancer:
Dr. Eli Rosenbaum – Head of Urological Oncology Department, Beilinson Hospital (Rabin)
Dr. Andrey Nadu – Head of the Laparoscopic Surgery Unit, Urology Department, Rabin Medical Center
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Diagnosis and treatment of renal cancer
Different types of kidney cancers develop in different ways, and this means that diseases have different predictions, diagnosed and treated in different ways.
Renal cell carcinoma (RCC) accounts for approximately 80 % of primary kidney tumors, urothelial carcinoma at UCC account for most other causes.
Other types of kidney cancer are:
Squamous cell carcinoma
Juxtaglomerular cell tumor (reninoma)
Wilms’ tumor (usually occurs in children under the age of 5 years)
Mixed epithelial – stromal tumor
Bellini channels carcinoma
Very rarely occur in kidney potentially malignant tumors which usually formed in other organs. These include:
Carcinoid tumors of the renal pelvis
Transitional cell carcinoma
Kidney cancer may also be secondary the result of metastasis of the primary tumor in other parts of the body.
Kidney cancer forms usually in two major areas: the renal tubules and renal pelvis. Most cancers in the renal tubule are renal cell carcinoma and adenocarcinoma. Most cancers in renal pelvis are transitional cell carcinoma.
Signs and symptoms of kidney cancer
The most common signs and symptoms of kidney cancer are heaviness in the abdomen and/or blood in the urine (hematuria). Other symptoms may include fatigue, loss of appetite, weight loss, fever and profuse sweating, and persistent pain in the abdomen. Nevertheless, many of these symptoms may be caused by other diseases, as well as missing at all, especially in the early stages of the disease.
Risks and causes of kidney cancer
Factors that increase the risk of kidney cancer include smoking, regular use of painkillers, obesity; genetic predisposition, family history of kidney cancer, as well as dialysis, hepatitis C , previous treatment of testicular cancer or cervical cancer.
Diagnosis of Kidney Cancer
Biopsy tumor tissue and study it for cancer cells.
PET-CT – used in metastatic invasive cancer
Treatment of kidney cancer
Treatment of renal cell carcinoma is dependent on the type and stage of the disease. The main and most effective treatment is surgery. Chemotherapy and radiotherapy (irradiation) is not generally regarded as kidney cancer, in most cases, do not respond to these treatments.
Therefore, if the body no metastatic spread, usually doctor recommends a laparoscopic procedure to remove a kidney tumor, which achieves by minimal invasion into the body through a small puncture.
Indications for surgery are established in each individual case on the basis of examination carried out by experienced professionals in Israel.
Our experts will do everything possible to save the kidney, and in most cases tumors amenable to resection and healthy organ tissue is preserved. But sometimes, depending on the size of the tumor can be removed whole kidney.
Unfortunately, surgery is not always possible. For example, the patient may show other diseases affecting the execution of the operation, or the cancer has spread to other organs and doctors can no longer remove it.
In that case, if the operation is not possible, sometimes doctors use other methods, such as cryotherapy (freezing the tumor) or radiofrequency ablation (evaporation tumor).
Other treatment options include biological treatments (treatment with stem cells as well as natural substances from the body), immunotherapy, including interferon treatment. Immunotherapy has recently shown a high potential and the ability to cause long-term complete remission or partial remission in many patients.
Wilms’ tumor when common treatments are chemotherapy, radiotherapy and surgery, depending on the stage of the disease.
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Renal cell carcinoma (RCC) treatment in Israel
Treatment of renal cell carcinoma (RCC) in Israel.
In recent years, there has been a steady increase in the incidence of kidney carcinoma all over the world and in Israel. Despite early detection of tumors, mortality from kidney cancer has also increased over the past two decades.
Carcinoma of the kidney (RCC) or renal cell carcinoma counts for about 80-70 percent of kidney cancer. About 98 percent of kidney cancer cases are accidental, and only 2 percent are associated with hereditary syndromes. Most kidney tumors are found during ultrasound or CT scan of the abdominal cavity, as a result of symptoms that are not necessarily associated with a kidney tumor. In the absence of other effective treatments, in Israel, removal of the tumor by surgery is the first major treatment in most cases.