Healthcare with Confidence
Leading Oncologist and Radiotherapy Specialist
Position: Senior Radiation Oncologist, Specialist in Oncology and Radiotherapy
Hospital: Assuta Hospital, Tel Aviv
Prof. Pfeffer is in the Forbes list of the best Israeli doctors
Dr. Raphael Pfeffer is a leading specialist in oncology with over 36 years of experience in radiation therapy. He is one of Israel’s most senior experts in radiotherapy and cancer treatment, with advanced international training in the United States.
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- Breast Cancer
- Prostate Cancer
- Head and Neck Cancer
- Brain Tumors
- Stereotactic Radiotherapy
- Combined Radiotherapy and Drug Therapy
Among the methods used by the doctor in Israel are intensity modulated radiation therapy, stereotactic radiosurgery for the removal of brain tumors, as well as extracranial stereotactic radiosurgery (tumors in the head, neck and other organs), the RapidArc method.
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Prof. Pfeffer is known for his personalized, precise approach to radiation therapy, combining it with advanced systemic treatments to improve patient outcomes.
Training & Education
- Advanced training in Radiation Oncology, Harvard University, Boston, USA
- Clinical fellowship, University of Michigan, Ann Arbor, USA
Professional Experience
- Former Director, Radiation Therapy Department, Sheba Medical Center (Tel HaShomer)
- Former Director, Oncology Institute, Assuta Hospital Tel Aviv
Academic & Research Involvement
- Contributor to leading international studies in radiotherapy
- Research interests include precision radiation, and integration with systemic treatments
Public Roles & Committee Work
- Former Treasurer, Israeli Oncology Society
- Chair, National Residency Committee in Radiotherapy
- Member of multiple international radiotherapy committees
- American Society of Therapeutic Radiation Oncology
- European Society of Therapeutic Radiation Oncology
- American Society of Clinical Oncology
- American Association for Cancer Research
- European Association of Neuro-Oncology
Languages Spoken
- Hebrew
- English
- French
Additional Services
- Private medical consultations
- Expert medical opinions for legal cases
Scientific Publications
Dr. Pfeffer is the author of more than 80 published articles on the clinical and research aspects of radiation therapy. His research projects include studying the effects of combined radiation therapy and chemotherapy, as well as the use of modern image-guided radiation therapy.
Here is a selection of peer-reviewed scientific publications authored or co-authored by Prof. Raphael Pfeffer, reflecting his extensive contributions to oncology and radiation therapy:
📚 Selected Publications
- The Interaction of Cisplatin Plus Etoposide With Radiation ± Hyperthermia, Pfeffer MR, Teicher BA, Holden SA, Al-Achi A, Herman TS
International Journal of Radiation Oncology, Biology, Physics, 1990; 19:1439–1447. This study explores the combined effects of cisplatin and etoposide with radiation therapy, with or without hyperthermia, on cancer treatment efficacy. - A Phase II Study of Imatinib for Advanced Adenoid Cystic Carcinoma of Head and Neck Salivary Glands. Pfeffer MR, Talmi Y, Catane R, Symon Z, Yosepovitch A, Levitt M. Oral Oncology, 2007; 43(1):33–36. This clinical trial assesses the efficacy of Imatinib in treating advanced adenoid cystic carcinoma of the salivary glands.
- High Incidence of Fistula Formation During Bevacizumab Treatment in Rectal Cancer Patients. Wolf I, Urban D, Pfeffer R, Catane R, Aderka D. Acta Oncologica, 2007; 46(4):550–553. This letter reports on the increased risk of fistula formation in rectal cancer patients undergoing Bevacizumab treatment.
- Adjuvant Radiotherapy for Thymic Epithelial Tumor: Treatment Results and Prognostic Factors. Kundel Y, Yellin A, Popovtzer A, Pfeffer R, Symon Z, et al. American Journal of Clinical Oncology, 2007; 30(4):389–394. This research evaluates the outcomes and prognostic factors associated with adjuvant radiotherapy in thymic epithelial tumors.
- Chemo-Radiotherapy of Oligometastases of Colorectal Cancer with Pegylated Liposomal Mitomycin-C Prodrug (PROMITIL): Mechanistic Basis and Preliminary Clinical Experience. Tahover E, Bar-Shalom R, Sapir E, Pfeffer R, et al. Frontiers in Oncology, 2018; 8:544. This study discusses the use of PROMITIL as a radiosensitizer in the treatment of colorectal cancer oligometastases.
- Pancreatic Cancer Outcome—Local Treatment with Radiation Using MRI-LINAC. Almog G, Pfeffer RM, Zalmanov S, et al. Frontiers in Oncology, 2023; 13:1289919. This article examines the outcomes of pancreatic cancer treatment using MRI-guided linear accelerator (MRI-LINAC) technology.
- Salvage Prostatic Fossa Radiation Therapy for Biochemical Failure After Radical Prostatectomy: The Sheba Experience. Kundel Y, Pfeffer R, Lauffer M, Ramon J, Catane R, Symon Z. Israel Medical Association Journal, 2004; 6(6):329–331. This study reviews the efficacy of salvage radiation therapy in patients experiencing biochemical failure post-radical prostatectomy.
- Lung Cancer in Israel. Grinberg RD, Refaely Y, Boehm Cohen L, Shaham D, Dudnik E, Pfeffer R, Allen A, Peled N. Journal of Thoracic Oncology, 2020; 15(4):493–498. This editorial provides an overview of lung cancer incidence and treatment approaches in Israel.
- Editorial: Radiation Therapy Using MRI-LINAC – The Right Way to Start: A Guide for Physicians and Physicists, Volume II. Pfeffer RM, Oyzar E, David MAB. Frontiers in Oncology, 2024; 14:1487081
and others.
