Skin cancer is the uncontrolled growth of abnormal skin cells with damaged DNA structure. These cells proliferate and form a cancerous tumor.
Israeli cancer physicians have a lot of experience in treating all types of skin cancer. Thanks to timely diagnosis and proper treatment, most types of skin cancer do not pose a danger to the lives of our patients.
The most aggressive type of skin cancer is melanoma, which at the progressive stage metastasizes to other organs. But even in this case, with the right approach the chances of recovery are very high, thanks to advanced methods of melanoma treatment in Israel.
We recommend a doctor for treatment of each specific type of skin cancer. This makes treatment most effective and helps to improve life quality of our patients.
Prof. Jacob Schachter – Head of the Ella Lamelbaum Institute for Melanoma and Immunooncology at Sheba Academic Medical Center, Chaim Sheba Hospital, Israel.
Deputy Director of Oncology Department of Chaim Sheba Hospital.
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The main types of skin cancer:
♦ Squamous Cell Carcinoma
♦ Basal cell carcinoma (basalioma)
♦ Actinic keratosis
♦ Dysplastic nevi ( atypical mole)
The first step toward the effective treatment is a correct diagnosis. All the patients should be examined in Israel.
Skin cancer diagnostics:
♦ Blood test
♦ Biopsy and histological examination of tissue
♦ Consultation oncologist
♦ Surgical consultation (in the case of indications for tumor resection)
Diagnosis usually lasts 4-5 days, after which the patient receives a conclusion from the doctor about the diagnosis.
Squamous cell carcinoma (SCC) – accounts for about 20% of skin cancer cases. This tumor usually grows slowly, but may be more aggressive and sometimes spread metastases. Squamous cell carcinoma looks like an unhealed wound, a lump on the skin, or a scaly area. In some cases, squamous cell carcinoma can grow very quickly and cause significant local injury. Squamous cell carcinoma is most aggressive when it develops on the lip and mucous of the oral cavity and tongue. This phenomenon is more common in smokers and requires alertness and referral to a doctor in all cases when there is a non-healing wound in the mouth or on the lips. The risk factors for the development of squamous cell carcinoma, as well as for basal cell carcinoma, are light skin, exposure to the sun, and elder age, usually older than 60 years. As with basal cell carcinoma, different types of treatment are used for squamous cell carcinoma, starting from ointments and ending with surgery (Mohs surgery), radiation therapy and, in extreme cases, chemotherapy.
Basal cell carcinoma – is an abnormal, uncontrolled growth of damaged basal cells, which are in the deepest layer of the epidermis (the top layer of skin). Basal cell carcinoma often looks like an open wound, red spot, pink blotch, shiny bump or scar. Typically basalioma does not metastasize to other organs. Metastatic process of this tumor is very rare.
After the dermatoscope diagnosis examination basal cell carcinoma should be confirmed by taking a biopsy and histological study in laboratory. If tumor cells are present, urgent treatment is necessary.
Dysplastic nevi ( atypical mole) – formed of melanocytic cells and , in some cases , is transformed into melanoma. This , in large part, depend on the genetic predisposition of the patient. Diagnosed dysplastic nevus using dermatoscope and biopsy studies , and subject to immediate surgical removal . In the future , such patients are at increased risk of developing melanoma , which requires an annual regular inspection dermatologist.
Actinic keratosis, also known as solar keratosis, is a solid lesions form that most often appear on the head, face, ears, lips, back of the hands and forearms, shoulders, neck, or any other parts of the body that are often abused exposed to the sun. Keratosis is a precursor to skin cancer and can go into an aggressive form of cancer, so the detection of the disease, it must be treated immediately.
Such disease is diagnosed using the dermatoscope, which allows a dermatologist to determine this type of cells at the microscopic level.
Treatment method is determined based on the type, size, location, and depth of penetration of the tumor, patient’s age and general state of health
“Bottleneck” surgical excision. In this case surgeon removes the minimum amount of tissue is completely excised cancer cells. This minimally invasive procedure is easy to stand and leaves scars in small sizes, which disappear with time. The procedure is performed on an outpatient basis in the doctor’s office and does not require hospitalization. In case of removal of large melanoma, skin transplantation produced by the patient with other body parts, which are generally not exposed and is not visible to outside.
Mohs micrographic surgery. The essence of this operation is to remove a thin layer of skin in one micrographic excision under control. Excision is terminated at the time when a precision microscope longer detects skin cancer cells. This method can detect cancer cells in the layers of skin that are invisible to the naked eye, and at the same time to preserve as much healthy tissue. In recent years, increasingly used in step mos staining to identify cancer cells. In such immunocytochemical or immunohistochemical staining using dyes that are absorbed predominantly skin pigment cells (melanocytes) of which melanoma formed, allowing them to be seen clearly under the microscope.
Radiotherapy. In some cases, treatment of basal cell carcinoma in destroying the tumor is exposed to X-rays, without the need for surgery and anesthesia. Total destruction formation is usually achieved by several treatments per week for several weeks. Radiation treatment is used in cases where there is a contraindication to surgical methods, such as the elderly or patients general condition which does not allow for surgery. This method gives a 90 percent cure rate, but entails some complications in the form of long-term cosmetic problems.
Cryosurgery. Method of freezing the tumor tissue with liquid nitrogen is used less frequently than all of the above methods, due to its lower efficiency. It is used only by the physician and usually in patients with bleeding disorders or intolerance to anesthesia.
Photodynamic therapy (PDT). Laser treatment. These methods are used as secondary therapy when other methods are unsuccessful , as well as in those with recurrent disease. In the Israeli medicine such treatment is not widely used due to its lower efficiency .
Immunotherapy. Interferon contain drugs (also used for the prevention of relapse)
Chemotherapy. In extremely rare cases of metastatic basal cell carcinoma or locally advanced basal cell carcinoma, when this type of cancer becomes life-threatening, applied chemotherapy. But such a method is used in cases where the nature of the condition excludes the use of other embodiments (e.g., surgery or radiation treatment).
When keratosis usually assigned special creams and solutions are applied to diseased skin for several weeks. This may be interferon stimulating drugs non-steroid antiinflammatory agents, in some cases, a laser and photodynamic therapy.
Method of treatment is determined individually for each patient by the physician. On the basis of a complete picture of the survey determined the prevalence of the process in the body , the degree of aggressiveness of the tumor , the individual characteristics of the organism (sensitivity to drugs , as well as the sensitivity of tumor cells to certain drugs ) , the general condition of the patient. Treatment can be in one of the above methods , and combine several techniques consistently.
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